| NURTuRE-INS |
NURTuRE Biobank is a national kidney biobank, developed through collaboration involving charity, academic and industry, under the strategic oversight and management of Kidney Research UK. The biobank ...
NURTuRE Biobank is a national kidney biobank, developed through collaboration involving charity, academic and industry, under the strategic oversight and management of Kidney Research UK. The biobank includes biological samples (plasma, serum, urine, DNA and tissue) and anonymised linked clinical data (through the UK Renal Registry) from 3000 patients with CKD and over 700 patients with INS. Samples are collected and centrally stored under strict Standard Operating Procedures
Read More
|
Idiopathic Nephrotic Syndrome ; INS |
Demographics ; Phenotype ; Genomics ; Transcriptomics ; Proteomics |
nurture@kidneyresearchuk.org |
|
| Abstract |
NURTuRE Biobank is a national kidney biobank, developed through collaboration involving charity, academic and industry, under the strategic oversight and management of Kidney Research UK. The biobank includes biological samples (plasma, serum, urine, DNA and tissue) and anonymised linked clinical data (through the UK Renal Registry) from 3000 patients with CKD and over 700 patients with INS. Samples are collected and centrally stored under strict Standard Operating Procedures |
| Research Study |
NURTuRE-INS |
| Data Types |
Demographics ; Phenotype ; Genomics ; Transcriptomics ; Proteomics |
| Keywords |
Idiopathic Nephrotic Syndrome ; INS |
| Age Range |
0 - 100 |
| Study Size |
739 |
| Controller |
UK Renal Registry and University of Bristol |
| Access Rights |
https://nurturebiobank.org/information-for-researchers/applying-for-data-and-samples/ |
| Legal Jurisdiction |
United Kingdom (UK) |
| Organisation |
Kidney Research UK |
| Contact Point |
nurture@kidneyresearchuk.org |
| Created At |
2024-09-11 14:56:00 |
| Modified At |
2024-09-11 14:56:00 |
| HDR Consent |
1 |
| Researchers |
| 1 : Prof Moin Saleem |
| Email |
M.Saleem@bristol.ac.uk |
| Affiliation |
University of Bristol ; Bristol Royal Hospital for Children ; Kidney Research UK |
| Publications |
| 1 : National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS study) |
| First Author |
E. Colby |
| Publication Journal |
Clin Kidney J |
| Publication Date |
2024 |
| Publication DOI |
10.1093/ckj/sfae096 |
|
| NURTuRE-CKD |
NURTuRE Biobank is a national kidney biobank, developed through collaboration involving charity, academic and industry, under the strategic oversight and management of Kidney Research UK. The biobank ...
NURTuRE Biobank is a national kidney biobank, developed through collaboration involving charity, academic and industry, under the strategic oversight and management of Kidney Research UK. The biobank includes biological samples (plasma, serum, urine, DNA and tissue) and anonymised linked clinical data (through the UK Renal Registry) from 3000 patients with CKD and over 700 patients with INS. Samples are collected and centrally stored under strict Standard Operating Procedures.
Read More
|
CKD ; Chronic Kidney Disease |
Demographics ; Phenotype ; Transcriptomics ; Proteomics |
nurture@kidneyresearchuk.org |
|
| Abstract |
NURTuRE Biobank is a national kidney biobank, developed through collaboration involving charity, academic and industry, under the strategic oversight and management of Kidney Research UK. The biobank includes biological samples (plasma, serum, urine, DNA and tissue) and anonymised linked clinical data (through the UK Renal Registry) from 3000 patients with CKD and over 700 patients with INS. Samples are collected and centrally stored under strict Standard Operating Procedures. |
| Research Study |
NURTuRE-CKD |
| Data Types |
Demographics ; Phenotype ; Transcriptomics ; Proteomics |
| Keywords |
CKD ; Chronic Kidney Disease |
| Age Range |
54 - 74 |
| Study Size |
2996 |
| Controller |
University of Nottingham |
| Access Rights |
https://nurturebiobank.org/information-for-researchers/applying-for-data-and-samples/ |
| Legal Jurisdiction |
United Kingdom (UK) |
| Organisation |
Kidney Research UK |
| Contact Point |
nurture@kidneyresearchuk.org |
| Created At |
2024-07-16 16:10:00 |
| Modified At |
2024-09-11 14:56:57 |
| HDR Consent |
1 |
| Researchers |
| 1 : Prof Maarten Taal |
| Email |
M.Taal@nottingham.ac.uk |
| Affiliation |
University of Nottingham |
| Publications |
| 1 : Associations with baseline blood pressure control in NURTuRE-CKD |
| First Author |
B.J.Lucas |
| Publication Journal |
Kidney International Reports |
| Publication Date |
2024 |
| Publication DOI |
https://doi.org/10.1016/j.ekir.2024.02.013 |
| 2 : A note on performance metrics for the kidney failure risk equation |
| First Author |
O.Alund |
| Publication Journal |
Nephrology Dialysis Transplantation |
| Publication Date |
2024 |
| Publication DOI |
https://doi.org/10.1093/ndt/gfae098 |
| 3 : Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease |
| First Author |
A.J.Osborne |
| Publication Journal |
npj Systems Biology and Applications |
| Publication Date |
2024 |
| Publication DOI |
https://doi.org/10.1038/s41540-024-00350-8 |
| 4 : Potentially modifiable factors associated with health-related quality of life among people with chronic kidney disease: baseline findings from the National Unified Renal Translational Research Enterprise CKD (NURTuRE-CKD) cohort |
| First Author |
T.Phillips |
| Publication Journal |
Clinical Kidney Journal |
| Publication Date |
2024 |
| Publication DOI |
https://doi.org/10.1093/ckj/sfae010 |
| 5 : Associations with age and glomerular filtration rate in a referred population with chronic kidney disease: methods and baseline data from a UK multicentre cohort study (NURTuRE-CKD) |
| First Author |
M.W.Taal |
| Publication Journal |
Nephrol Dial Transplant |
| Publication Date |
2023 |
| Publication DOI |
https://doi.org/10.1093/ndt/gfad110 |
| Use Conditions |
| Allowed Countries |
United Kingdom (UK) |
| Profit Use |
No |
| Broad Research Use |
Biomedical Research |
| Specific Research Use |
Research on fundamental biology ;Research on genetics ;Research on drug development ;Research on age categories ;Research on gender categories |
| Recontact |
No |
|
CYCLE-HD |
CYCLE-HD trial data
CYCLE-HD trial data
|
chronic kidney disease ; dialysis ; exercise ; MR heart |
Imaging |
jb343@le.ac.uk |
|
| Abstract |
CYCLE-HD trial data |
| Theme |
Cardiovascular |
| Research Study |
Cycle HD study |
| Data Types |
Imaging |
| Funders |
NIHR |
| Keywords |
chronic kidney disease ; dialysis ; exercise ; MR heart |
| Age Range |
18 - 100 |
| Study Size |
130 |
| Controller |
University of Leicester |
| Access Rights |
https://le.ac.uk/cardiovascular-sciences |
| Legal Jurisdiction |
United Kingdom (UK) |
| Organisation |
University of Leicester |
| Contact Point |
jb343@le.ac.uk |
| Created At |
2023-11-09 11:50:18 |
| Modified At |
2023-11-09 11:50:18 |
| HDR Consent |
1 |
| Researchers |
| 1 : Prof James Burton |
| Email |
jb343@le.ac.uk |
| Affiliation |
University of Leicester |
| Use Conditions |
| Allowed Countries |
United Kingdom (UK) |
| Profit Use |
No |
| Broad Research Use |
Biomedical Research |
| Recontact |
No |
|
LCC-CKD |
Leicestershire primary care chronic kidney disease dataset
Leicestershire primary care chronic kidney disease dataset
|
kidney ; CKD ; primary care ; cohort ; outcomes |
Demographics ; Phenotype ; comorbidities ; medications ; biochemistry ; blood pressure ; urine biochem |
rwlm2@le.ac.uk |
|
| Abstract |
Leicestershire primary care chronic kidney disease dataset |
| Research Study |
Primary care chronic kidney disease cohort with five years of follow-up. Linked to secondary care cardiovascular and kidney outcomes. |
| Data Types |
Demographics ; Phenotype ; comorbidities ; medications ; biochemistry ; blood pressure ; urine biochem |
| Ethnicities |
White and Asian ; African ; Caribbean |
| Funders |
NIHR |
| Geographies |
Leicestershire |
| Keywords |
kidney ; CKD ; primary care ; cohort ; outcomes |
| Age Range |
18 - 100 |
| Study Size |
17248 |
| Controller |
University of Leicester |
| Access Rights |
https://academic.oup.com/ndt/advance-article-abstract/doi/10.1093/ndt/gfaa291/6095733?redirectedFrom=PDF |
| Legal Jurisdiction |
United Kingdom (UK) |
| Organisation |
University of Leicester |
| Contact Point |
rwlm2@le.ac.uk |
| Created At |
2023-11-09 10:00:51 |
| Modified At |
2023-11-09 10:00:51 |
| HDR Consent |
1 |
| Researchers |
| 1 : Dr Rupert Major |
| Email |
rwlm2@le.ac.uk |
| Affiliation |
University of Leicester |
| 2 : Prof Nigel Brunskill |
| Email |
njb18@le.ac.uk |
| Affiliation |
University of Leicester |
| Use Conditions |
| Allowed Countries |
United Kingdom (UK) |
| Profit Use |
No |
| Broad Research Use |
Method development ;Research on Population ;Biomedical Research |
| Recontact |
No |
|
| SCRIPT Study: linking immune phenotype to clinical outcome in long term kidney transplant recipients |
SCRIPT was a longitudinal case-control study of over 150 long term, Caucasian kidney transplant recipients, which recruited participants 2012-2014 and followed them up for 5 years. The main aim was t ...
SCRIPT was a longitudinal case-control study of over 150 long term, Caucasian kidney transplant recipients, which recruited participants 2012-2014 and followed them up for 5 years. The main aim was to identify immunological predictors of malignancy in this population. Outcomes of interest were graft function, graft loss, death and development of malignancy. Peripheral blood mononuclear cells (PBMC), serum and whole blood DNA/RNA were taken from patients at recruitment, 6 months and 12 months.
Read More
|
SCC ; Cancer ; Kidney Transplant ; Immunology |
Demographics ; Phenotype ; Transcriptomics ; Biochemical data |
Matthew.bottomley@ndm.ox.ac.uk |
|
| Abstract |
SCRIPT was a longitudinal case-control study of over 150 long term, Caucasian kidney transplant recipients, which recruited participants 2012-2014 and followed them up for 5 years. The main aim was to identify immunological predictors of malignancy in this population. Outcomes of interest were graft function, graft loss, death and development of malignancy. Peripheral blood mononuclear cells (PBMC), serum and whole blood DNA/RNA were taken from patients at recruitment, 6 months and 12 months. |
| Theme |
Lifestyle |
| Research Study |
SCRIPT (Skin Cancer and Regulatory Phenotype post-Transplant) Study |
| Data Types |
Demographics ; Phenotype ; Transcriptomics ; Biochemical data |
| Ethnicities |
English |
| Funders |
Wellcome Trust |
| Geographies |
Oxfordshire |
| Keywords |
SCC ; Cancer ; Kidney Transplant ; Immunology |
| Age Range |
29 - 79 |
| Study Size |
157 |
| Controller |
University of Oxford |
| Access Rights |
https://www.ndm.ox.ac.uk/team/matthew-bottomley |
| Legal Jurisdiction |
United Kingdom (UK) |
| Organisation |
University of Oxford |
| Contact Point |
Matthew.bottomley@ndm.ox.ac.uk |
| Created At |
2023-06-01 04:15:49 |
| Modified At |
2023-06-01 04:15:49 |
| HDR Consent |
1 |
| Researchers |
| 1 : Dr Matt Bottomley |
| Email |
matthew.bottomley@ndm.ox.ac.uk |
| Affiliation |
Oxford University Hospitals NHS Foundation Trust ; University of Oxford |
| Publications |
| 1 : Application of Operational Tolerance Signatures Are Limited by Variability and Type of Immunosuppression in Renal Transplant Recipients: A Cross-Sectional Study |
| First Author |
Matthew Bottomley |
| Publication Journal |
Transplant Direct |
| Publication Date |
2016 |
| Publication DOI |
10.1097/TXD.0000000000000638. |
| 2 : CD8+ Immunosenescence Predicts Post-Transplant Cutaneous Squamous Cell Carcinoma in High-Risk Patients |
| First Author |
Matthew Bottomley |
| Publication Journal |
Journal of the American Society of Nephrology |
| Publication Date |
2015 |
| Publication DOI |
10.1681/ASN.2015030250. |
| 3 : Dampened Inflammatory Signalling and Myeloid-Derived Suppressor-Like Cell Accumulation Reduces Circulating Monocytic HLA-DR Density and May Associate With Malignancy Risk in Long-Term Renal Transplant Recipients |
| First Author |
Matthew Bottomley |
| Publication Journal |
Frontiers in Immunology |
| Publication Date |
2022 |
| Publication DOI |
10.3389/fimmu.2022.901273 |
| Use Conditions |
| Allowed Countries |
United Kingdom (UK) |
| Profit Use |
No |
| Broad Research Use |
Biomedical Research |
| Specific Research Use |
Research on age categories ;Research on gender categories |
| Recontact |
No |
|
PSP-CKD data |
CKD data derived from trial of primary care intervention for CKD in Northants. 46 practices data
CKD data derived from trial of primary care intervention for CKD in Northants. 46 practices data
|
kidney ; chronic ; disease ; proteinuria ; nurse ; cluster ; outcomes ; longitudinal |
Demographic ; primary diagnosis ; comorbidities ; blood results ; medications ; urine results |
njb18@le.ac.uk |
|
| Abstract |
CKD data derived from trial of primary care intervention for CKD in Northants. 46 practices data |
| Theme |
Renal disease |
| Research Study |
PSP CKD Study |
| Data Types |
Demographic ; primary diagnosis ; comorbidities ; blood results ; medications ; urine results |
| Ethnicities |
unselected |
| Funders |
NIHR |
| Keywords |
kidney ; chronic ; disease ; proteinuria ; nurse ; cluster ; outcomes ; longitudinal |
| Age Range |
18 - 100 |
| Study Size |
46000 |
| Controller |
University of Leicester |
| Access Rights |
https://jasn.asnjournals.org/content/jnephrol/early/2019/05/15/ASN.2018101042.full.pdf?with-ds=yes%3Fversioned%3Dtrue |
| Legal Jurisdiction |
United Kingdom (UK) |
| Organisation |
University of Leicester |
| Contact Point |
njb18@le.ac.uk |
| Created At |
2023-03-29 12:29:52 |
| Modified At |
2023-03-29 12:29:52 |
| HDR Consent |
1 |
| Researchers |
| 1 : Prof Nigel Brunskill |
| Email |
njb18@le.ac.uk |
| Affiliation |
University of Leicester |
| 2 : Dr Rupert Major |
| Email |
rwlm@le.ac.uk |
| Affiliation |
University of Leicester |
| Publications |
| 1 : The Primary-Secondary Care Partnership to Improve Outcomes in Chronic Kidney Disease (PSP-CKD) Study: A Cluster Randomized Trial in Primary Care |
| First Author |
Major, R |
| Publication Journal |
J Am Soc Nephrol |
| Publication Date |
2019 |
| Publication DOI |
doi.org/10.1681/ASN.2018101042 |
| Use Conditions |
| Allowed Countries |
United Kingdom (UK) |
| Profit Use |
No |
| Broad Research Use |
Research on Population |
| Specific Research Use |
Research on fundamental biology |
| Recontact |
No |
|